The balanced minimum evolution problem under uncertain data
نویسندگان
چکیده
منابع مشابه
The balanced minimum evolution problem under uncertain data
We investigate the Robust Deviation Balanced Minimum Evolution Problem (RDBMEP), a combinatorial optimization problem that arises in computational biology when the evolutionary distances from taxa are uncertain and varying inside intervals. By exploiting some fundamental properties of the objective function, we present a mixed integer programming model to exactly solve instances of the RDBMEP a...
متن کاملThe Balanced Minimum Evolution Problem
A phylogeny is an unrooted binary tree that represents the evolutionary relationships of a set of n species. Phylogenies find applications in several scientific areas ranging from medical research, to drug discovery, to epidemiology, to systematics, and to population dynamics. In such applications the available information is usually restricted to the leaves of a phylogeny and is represented by...
متن کاملApproximating the balanced minimum evolution problem
We prove a strong inapproximability result for the Balanced Minimum Evolution Problem. Our proof also implies that the problem remains NP-hard even when restricted to metric instances. Furthermore, we give a MST-based 2-approximation algorithm for the problem for such instances.
متن کاملOptimal solutions for the balanced minimum evolution problem
Phylogenies are trees representing the evolutionary relationships of a set of species (called taxa). Phylogenies find application in several scientific areas ranging from medical research to drug discovery, epidemiology, systematics and population dynamics. In these applications the available information is usually restricted to the leaves of a phylogeny and is represented by molecular data ext...
متن کاملImproved Solutions for the Balanced Minimum Evolution Problem
The minimum evolution criterion is one of the most important criteria of molecular phylogenetic estimation. It states that the phylogeny of a given set of molecular data (taxa) is the one whose sum of edge weights is minimal. Finding the phylogeny that satisfies the minimum evolution criterion involves solving an optimization problem, called the Minimum Evolution Problem (MEP), whose versions a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Discrete Applied Mathematics
سال: 2013
ISSN: 0166-218X
DOI: 10.1016/j.dam.2013.03.012